Mastitis origin

Human mastitis origin The mamary gland of lactating women contains a physiological microbiota. However, there are different factors which can lead to infectious mastitis, the main medical cause of early weaning, which in turn may cause inflammation and obstruction of the ducts. Some mastitis may follow an acute course with severe symptomatology, both local and […]

Human mastitis origin

The mamary gland of lactating women contains a physiological microbiota. However, there are different factors which can lead to infectious mastitis, the main medical cause of early weaning, which in turn may cause inflammation and obstruction of the ducts. Some mastitis may follow an acute course with severe symptomatology, both local and systemic (fever, chills, swollen glands, sore muscles and joints, general discomfort,…), and even lead to abscess formation; the aetiological pathogens responsible for such cases is almost invariably, Staphylococcus aureus.

However, in the majority of cases of mastitis (subacute and chronic mastitis), symptoms are restricted to the mammary gland and are characterized by severe pain in the form of sharp pain, cramping or burning sensation, with or without injury to the nipple. On some occasions, mastitis can be subclinical and characterized by a false sense of decrease in milk production when, in reality, what is affected is the secretion due to clogged ducts. In the latter case, the causative agents tend to be coagulase-negative Staphylococci (mainly Staphylococcus epidermidis), some streptococcus species such as Streptococcus mitis or Streptococcus salivarius and some species from the Corynebacterium genus.

Bacteria that cause mastitis usually share some common properties: bio-film formation, resistance to clinically relevant antibiotics and the ability to avoid the immune response.

One of the main predisposing factors for the development of this infection is the use of antibiotics during the last third of pregnancy, labour and breastfeeding.

Extend schema Mastitis etiopatogenia